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Figure 5 shows the simulated fracture propagation process. Each column is a simulation result at a saturation. Saturation has a significant impact on fracture propagation and distribution. When saturation is high (), numerous cracks gathered near the initial hole and cross-cuttings occur between the cracks. The lower the saturation, the farther away the cracks spead from the initial hole and the fewer the number of cracks there is.
Patients randomized to the exercise training group participated in a structured, unsupervised exercise program individually prescribed based on heart rate reserve derived from the baseline cardiopulmonary exercise test. Exercise was initiated at a minimum of 3 sessions per week, 20 minutes per session, at a heart rate corresponding to 60% of heart rate reserve (resting heart rate +0/6 [maximal heart rate minus resting heart rate]). A rating of perceived exertion on the Borg scale22 was used as a secondary measure of goal exercise intensity, and participants were instructed to maintain an intensity correlating to perceived exertion ratings between 11 to 14, which correlates with a moderate level of intensity. The exercise prescription was designed to increase duration of exercise by 5 to 10 minutes every week, up to 60 minutes per session, 4 to 7 sessions per week, and then incrementally increase training intensity to a goal of 70% of heart rate reserve during the first month of the study protocol. Patients were instructed to maintain their exercise regimen from weeks 5 through 16 of the protocol. Modes of exercise included cycling, walk-jog protocols, and elliptical training. No strength training or burst-type activity was prescribed. Patients in the exercise group received a 1-hour exercise consultation with a certified exercise physiologist.
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The Scramble For Africa
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Exercise performance measures included other measures of exercise capacity, including exercise time, peak metabolic equivalent of tasks (METs), minute ventilation/carbon dioxide production (VE/Vco2) slope, and anaerobic threshold. Nonfatal arrhythmias including occurrence of nonsustained ventricular tachycardia (NSVT), atrial arrhythmias, and change in premature ventricular contraction (PVC) burden were also assessed. Major adverse events were defined as death, aborted sudden cardiac death, appropriate implantable cardioverter-defibrillator (ICD) shock, and sustained ventricular tachycardia.
Simulation of Hydraulic Fracture in Unsaturated Soils with High Degree of Saturation
First of all, if you like well-written non-fiction, particularly in the history genre (which, as I get older, I do more and more) then this book is up there with any I've ever read. Sweeping, epic, magnificent etc etc.
Extra attention is given to photosynthesis due to its importance in the field of renewable energy. This thoroughly revised and updated third edition focuses on the utilization of sustainable energy and mitigating climate change. The text explains the physical mechanisms behind climate change and discusses the physics of renewable energy options. Nuclear power is treated in a separate chapter because of its social and political importance. In the final chapter political and social aspects of ‘renewable energy and climate change' are reviewed. A distinguishing feature of the text is the discussion of spectroscopy and spectroscopic methods, again from basic concepts, as a crucial means to quantitatively analyze and monitor the condition of the environment, the factors determining climate change and all aspects of energy conversion. This textbook will be invaluable to students in physics and related subjects such as physical chemistry and geophysics. It assumes a basic knowledge in physics and mathematics, and all equations are derived from first principles and explained in a physical way.
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I read this book, or parts of the massive work, in my thirties and it opened up thirty five years of shocking greed, colonialism, corruption and human rights abuse in a compelling, detailed and straightforward way that I haven't encountered in so much detail afterwards. Since then I still revert back to it from time to time and it never seizes to amaze me.
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Starting with Galileo's experiments with motion, this study of 25 crucial discoveries includes Newton's laws of motion, Chadwick's study of the neutron, Hertz on electromagnetic waves, and more. Includes Isaac Newton's "The Laws of Motion," Henry Cavendish's "The Law of Gravitation," Heinrich Hertz's "Electromagnetic Waves," Niels Bohr's "The Hydrogen Atom," and more.
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Chang and Duncan present an extension of Biot’s theory which makes possible finite element analyses of the consolidation of inelastic, unsaturated soil masses. The basic equations governing consolidation may be stated as follows.
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The story contains multiple number of characters, where the most attention gets the Belgian King Leopold. His actions are costumed in virtuous humanitarianism showing that he is the catalyst for the motivation on the exploitation of Africa.
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In this paper, the Biot’s consolidation theory is used as a framework that governs the interactions between the soil skeleton and the pore fluid. The concept of homogenized pore fluid is used to describe water-air mixture fluid. The nonlinear constitutive relationship developed by Duncun and Chang is used to describe the soil deformation for its simplicity. The finite element method (FEM) is employed to discretize the Biot equation. The FEM is chosen because it can readily obtain the solutions of boundary value problems on nonconformal domains.
Histone methylation mainly acts on lysine residues and regulates either the repression or activation of gene expression. You can picture this high chalk country as an open hand, the left hand, with Salisbury in the hollow of the palm, placed nearest the wrist, and the five valleys which cut through it as the five spread fingers, from the Bourne (the little finger) succeeded by Avon, Wylye, and Nadder, to the Ebble, which comes in lower down as the thumb and has its junction with the main stream below Salisbury. Rooms start around $900 per night, making this a very popular choice with budget minded families.
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The prize-winning essays in this book address the fascinating but sometimes uncomfortable relationship between physics and mathematics. Is mathematics merely another natural science? Or is it the result of human creativity? Does physics simply wear mathematics like a costume, or is math the lifeblood of physical reality? The nineteen wide-ranging, highly imaginative and often entertaining essays are enhanced versions of the prize-winning entries to the FQXi essay competition “Trick or Truth”, which attracted over 200 submissions. The Foundational Questions Institute, FQXi, catalyzes, supports, and disseminates research on questions at the foundations of physics and cosmology, particularly new frontiers and innovative ideas integral to a deep understanding of reality, but unlikely to be supported by conventional funding sources.
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I think is probably about as good an overview of European exploitation of Africa over a 40-year stretch as it is possible to write. The characters are vivid, it provides agency and humanity to all the characters (even those who it is pretty impossible to understand), and keeps things moving in an entertaining fashion.
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The nonlinear elastic model proposed by Duncan and Chang is used as the constitutive relationship for solids. The main features of the model are summarized here.
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I kind of feel like, yeah, I want to go home, but then I think to myself what am I going to do when I get home. Am I just going to go back to what I’ve been doing?
This was my third attempt to read The Scramble for Africa by Thomas Pakenham and turns out third time really is the charm. Based on the stellar reviews, I had high hopes for this book but for me it has been a frustrating experience. For the most part my unhappiness stems from the fact I wanted this to be a comprehensive history of Africa and how the colonisation shaped the continent.
This was a truly remarkable read. It's not an easy book, it's very long and each page contains a great deal of information. This lecture needs to be slow and thorough as through it you lay the foundations of the understanding of Africa.
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The results provide a numerical picture depicting the mechanisms of crack initiation and propagation during hydraulic fracturing. The numerical results are in good agreement with the experimental results, which confirms the adequacy and the power of the numerical approach.
A comprehensive look at how Africa became colonized. The surprising part is how late in the 19th Century it actually happened. Another is how Belgium, created as a "buffer state" between France and Germany and ruled by one of Victoria's favorite uncles, became a major player. The events in this book lead to actions and reactions that are still being played out on the continent of Africa.
Introduction to Solid State Ionics: Phenomenology and Applications presents a pedagogical, graduate-level treatment of the science and technology of superionic conductors, also known as fast ion conductors or solid electrolytes. Suitable for physics, materials science, and engineering researchers and students, the text emphasizes basic physics and chemistry as well as applications of electrochemical energy materials. The book focuses on fundamental phenomenological aspects, including crystal structure, phonon dispersion, electronic band structure, defects, disorder, nonstoichiometry, non-equilibrium thermodynamics, phase transitions, and statistical mechanics of iono-electron transport. It explains how the design, synthesis, and characterization of materials aid in optimizing diffusion coefficients and ionic conductivities. The author also describes important applications of solid state ionics, including solid state batteries, fuel cells, and electrochemical sensors.
I read this book back when it first appeared. It is a bit of a slog but I still remember the story today and I have not found an account of the enhanced colonial acquisition of Africa leading up to WW1 that surpasses this book, although there are fine accounts for particular people and regions. I remember few books as I do this one.
This massive book (738 pages plus photos & maps) offers the reader an interesting and enjoyable account of the European powers race to 'civilize' the African continent. The book covers the great explorers, the numerous battles and conflicts (between the European powers and the natives and between the European powers) and many other interesting items during this 'scramble for Africa'. I found this book to be a great read, very enjoyable and although the size may be daunting it never got boring.
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Patients randomized to the usual-activity group were not provided with a formal exercise prescription at study entry and were instructed to continue their current activity practices through the duration of the study without any exercise directives. As an incentive for participation, patients in the usual-activity group were provided with an exercise consultation and exercise prescription at the conclusion of the study protocol.
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For Chapters 1-14, this manual contains detailed solutions to approximately 12 problems per chapter. These problems are indicated in the textbook with boxed problem numbers. The manual also features a skills section, important notes from key sections of the text, and a list of important equations and concepts.
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Fracture toughness has been introduced as a parameter that could possibly be used to indicate the onset of propagation. If it is a material property, fracture toughness must be independent of slot length. It can depend on saturation, however, although the dependence is expected to be similar to other properties that also depend on saturation.
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The primary outcome was change in peak V̇o2 from baseline to week 16. Secondary outcomes included measures of change in cardiac remodeling, QOL, and exercise performance. Cardiac remodeling measures included magnitude of cardiac hypertrophy, left ventricular chamber dimensions, systolic and diastolic function, and scar volume as assessed by a combination of echocardiography and cardiac magnetic resonance imaging (CMR), plasma B-type natriuretic peptide concentration, and degree of LVOT obstruction.
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The concept of a “homogenized pore fluid” is that this mixture of gas and liquid can be considered to be an equivalent homogeneous pore fluid which completely fills the pores of the soil. As the proportions of air and water vary (due to flow of water and air, or due to compression of air and dissolution of air), the mechanical properties of the homogenized pore fluid vary. The compressibility of the pore fluid and changes in the degree of saturation due to changes in pore fluid pressure may be calculated using Boyle’s Law and Henry’s Law .
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Fifth, the exercise prescription used in this study only incorporated moderate-intensity aerobic exercise in adult patients. Future studies will need to address the safety and benefits of more vigorous aerobic exercise and isometric activities, including participation in competitive sports, in both adult and pediatric patients with hypertrophic cardiomyopathy.
Two approaches, namely, the discrete crack model and the smeared crack model were introduced to FEM by Ngo and Scordelis and Rashid , respectively. The discrete crack model is aimed at simulating the initiation and propagation of dominant cracks. In contrast, the smeared crack model is based on the idea that many small cracks nucleate which only in a later stage of the loading process link up to form one or more dominant cracks.
The primary research team for this community-based project consisted of clinicians and community and academic researchers. The study was conducted in collaboration with housing, healthcare, and HIV service providers and was advised by 2 individuals with lived experience of discharge from Casey House. Community members with lived experience attended team meetings, provided feedback on all stages of the project (ie, interview guides, recruitment, analysis and dissemination), and helped facilitate community engagement sessions with other patients at the start and the end of the project.
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The pores of an unsaturated soil are filled partly with gas (air) and partly with liquid (water), and the air phase might be present in an unsaturated soil either in a continuous or an occluded (bubbles) form. An important and frequently encountered special case is that in which the degree of saturation is sufficiently high so that the air bubbles are occluded. This condition prevails at degrees of saturation greater than about 0/85, which is common in many practical cases.
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The discharge process was often perceived by participants to be rushed. Some participants found the discharge meetings helpful, while others did not feel the process empowered them to engage in a meaningful conversation with hospital staff.
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We used a multi-case study approach to explore the discharge process and post-discharge period. A case was defined as the discharge and transition of a patient from hospital to community. Data were collected through serial interviews with patients (n = 4), medical chart abstraction, and review of discharge summaries. Serial interviews, although not frequently used in clinical research, have been proposed as a strong approach for exploring complex processes and to build trust between researcher and participant,19 both of which were relevant in this study. Patient interviews were conducted by the Master’s trained research coordinator (SM) using tailored semi-structured interview guides for 4 time points: before the discharge meeting (I1); after the discharge meeting but before discharge (I2); within a week of discharge (I3); and approximately 30 days after discharge (I4). Interviews were audio recorded and transcribed verbatim.
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A brilliantly constructed narrative that weaves together the many narrative threads of the various European powers grabbing pieces of Africa, occasionally coming into conflict with each other, or the local population. Provides valuable context on how the map of modern Africa developed, and a lesser known chapter in world history of the 19th century.
One of my favourite movies is ‘Zulu’ but what you don’t learn in that movie but will from this book is that the Zulus weren’t the aggressors - the Boers and British were. Like so much of history, the past has been rewritten by the victor and much of relevance has been left out or is barely known.
Standard practice for discharge planning involves clinicians determining a tentative discharge date and identifying strategies to support the patient. Planning is informed by knowledge gathered by the interdisciplinary team throughout the admission, including social determinants of health (ie, housing, social support, food security). Patients are encouraged to invite an individual from their social support network to attend a discharge meeting, where the care team reviews goals for admission, course of treatment, referrals, and important follow-up dates.
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However, Sparks has shown that can assume values greater than unity, and that it can also be negative. Coleman , Blight , and Matyas and Radharkrishna have shown that the value of applicable to volume change behaviour is different from the value of applicable to the strength behaviour of the same soil at the same degree of saturation. This fact indicates that (2) is not fundamentally valid and is not likely to be applicable except under limited ranges of conditions and for limited purposes.
Hydraulic fracturing may be defined as the process of creating a fracture or fracture system in a porous medium by injecting a fluid under pressure through a well bore in order to overcome native stresses. Hydraulic fracturing has been used for more than 50 years to enhance the yield of wells recovering oil at great depth. In the recent past, hydraulic fracturing methods have been developed for creating fractures in soils and making existing fractures larger to enhance the mass transfer of contaminants. The fractures created increase the effective permeability and change paths of fluid flow, thus making in situ remediation more effective and economical. Hydraulic fracturing appears to have useful environmental, agricultural and geotechnical applications.
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Both of the preceding effective stress equations involve difficulties for practical application. The concept of a “homogenized pore fluid” presented by offers a simple alternative to these equations which is applicable for a limited but useful range of conditions.
Hydraulic fracturing techniques are equally applicable to both saturated soils and unsaturated soils to improve the flow of water and air, respectively. Earth’s land is mostly located in the unsaturated vadose zone above the water table, so the hydraulic fracturing of unsaturated soil has important significance. An unsaturated soil is commonly referred to as a 3-phase system composed of solids (soil particles), water, and air.
Fracture toughness appears to be independent of the length of the starter slot in the range and to be dependent of the length of the starter slot in the range under the conditions used here. Increase of the length of the starter slot can decrease this dependence.
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I started this for the oddest of reasons: the author is from my hometown (sort of). Thomas Pakenham is the 8th Earl of Longford, whose family seat is Tullynally Castle, a few kilometers west of Castlepollard, Co. Westmeath. Besides being an internationally renown historian, he's also an arborist and brother to the novelist Antonia Frasier.
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This textbook provides conceptual, procedural, and factual knowledge on solid state and nanostructure physics. It is designed to acquaint readers with key concepts and their connections, to stimulate intuition and curiosity, and to enable the acquisition of competences in general strategies and specific procedures for problem solving and their use in specific applications. To these ends, a multidisciplinary approach is adopted, integrating physics, chemistry, and engineering and reflecting how these disciplines are converging towards common tools and languages in the field. Each chapter discusses essential ideas before the introduction of formalisms and the stepwise addition of complications. Questions on everyday manifestations of the concepts are included, with reasoned linking of ideas from different chapters and sections and further detail in the appendices. The final section of each chapter describes experimental methods and strategies that can be used to probe the phenomena under discussion. Solid state and nanostructure physics is constantly growing as a field of study where the fascinating quantum world emerges and otherwise imaginary things can become real, engineered with increasing creativity and control: from tinier and faster technologies realizing quantum information concepts, to understanding of the fundamental laws of Physics. Elements of Solid State Physics and of Crystalline Nanostructures will offer the reader an enjoyable insight into the complex concepts of solid state physics.
Epub 2020 Oct 8. Authors Christian P Selinger 1, Gareth C Parkes 2, Ash Bassi 3, Jimmy K Limdi 4, Helen Ludlow 5, Pritash Patel 6, Melissa Smith 7, Santosh Saluke 8, Zandile Ndlovu 9. T2-E8 The Realest Prez President Obama Brings Out Key From Key & Peele For His White House Correspondents' Dinner Speech. Fine cast of characters from uptight.
Shattered by his lover Jason’s suicide, archaeologist Dan Logan is struggling to patch his life together again. He’s desperately following up Jason’s final obsession, a secret buried deep within the military zone on Salisbury Plain. Anything is better than facing the void of his grief.
An incredibly detailed and sometimes very hard to push through read. It is rewarding if you have patience with it, and I imagine it feels much like an encyclopedia to someone who is more familiar with the subject. Would recommend to any proper history nerd.
A post hoc sensitivity analysis of the primary outcome was performed by multiple imputation with 10 interactions on all patients randomized by using demographics, baseline characteristics, baseline comorbidities, and baseline cardiopulmonary exercise test parameters. Linear regression was performed on the change in peak V̇o2, adjusting for baseline value. In additional post hoc analyses, submaximal exercise studies, defined as those with peak respiratory exchange ratio less than 1/05, were removed from the primary end point analysis and analysis of variance was performed. To control for variability in peak effort, V̇o2 attained at respiratory exchange ratio 1/0 was analyzed by group. Comparison of the PVC burden over time also was performed.
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However, many assumptions and simplifications are made in existing numerical studies; for example, fissures need to be placed inside the analyzed domain prior to analysis [19, 20] or the hardening of grout in soil cannot be described . A numerical model for coupled analysis of flow, stress, and damage was proposed to overcome the shortcoming of the placing of preset of fractures . The approach is similar to smeared crack method. The simulated domain is discretized into large numbers of tiny elements to take into account the small local variations of the material properties. At each loading step, the stress and strain in the elements are calculated and examined against the predefined soil strength. Those elements with the stresses above the material’s strength were considered to be isotropically damaged. The material properties of the damaged element are reduced and the width of the facture in the damaged element can be calculated. This approach can effectively simulate hydraulic fracturing [22–24] in rocks. In this paper, the extension of the approach for rocks to unsaturated soil is attempted so that hydraulic fracturing in unsaturated soil can be numerically simulated.
Consolidation appears to toughen the clay, according to simulation results of samples consolidated for 4 days and 14 days under a static pressure of 69 kPa. The of the samples consolidated for 14 days is greater by 6/1 than the of 4 days consolidated samples at similar and m. With the increase of saturation, the difference of is reduced, which means that the tough effect of consolidation is weakened.
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The findings from this randomized clinical trial provide support for moderate-intensity aerobic exercise for improving exercise capacity in patients with hypertrophic cardiomyopathy. The magnitude of improvement in peak V̇o2 was modest, with an absolute increase of 1/27 (95% CI, 0/17 to 2/37) mL/kg/min in the exercise training group compared with the usual-activity group, representing an absolute increase of 6% (95% CI, 1/27% to 22/7%).